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Leishmaniasis, New World

MedGen UID:
39243
•Concept ID:
C0086540
•
Disease or Syndrome
Synonyms: American Leishmaniasis; Leishmaniasis, American; New World Leishmaniasis

Professional guidelines

PubMed

Drug resistance and treatment failure in leishmaniasis: A 21st century challenge.
Ponte-Sucre A, Gamarro F, Dujardin JC, Barrett MP, López-Vélez R, García-Hernández R, Pountain AW, Mwenechanya R, Papadopoulou B
PLoS Negl Trop Dis 2017 Dec;11(12):e0006052. Epub 2017 Dec 14 doi: 10.1371/journal.pntd.0006052. PMID: 29240765Free PMC Article
Current diagnosis and treatment of cutaneous and mucocutaneous leishmaniasis.
Goto H, Lindoso JA
Expert Rev Anti Infect Ther 2010 Apr;8(4):419-33. doi: 10.1586/eri.10.19. PMID: 20377337
Treatment of New World cutaneous leishmaniasis--a systematic review with a meta-analysis.
Tuon FF, Amato VS, Graf ME, Siqueira AM, Nicodemo AC, Amato Neto V
Int J Dermatol 2008 Feb;47(2):109-24. doi: 10.1111/j.1365-4632.2008.03417.x. PMID: 18211479

Recent clinical studies

Etiology

Cutaneous Leishmaniasis: A 2022 Updated Narrative Review into Diagnosis and Management Developments.
de Vries HJC, Schallig HD
Am J Clin Dermatol 2022 Nov;23(6):823-840. Epub 2022 Sep 14 doi: 10.1007/s40257-022-00726-8. PMID: 36103050Free PMC Article
Cutaneous and mucocutaneous leishmaniasis: Clinical perspectives.
Handler MZ, Patel PA, Kapila R, Al-Qubati Y, Schwartz RA
J Am Acad Dermatol 2015 Dec;73(6):897-908; quiz 909-10. doi: 10.1016/j.jaad.2014.08.051. PMID: 26568335
The immunological, environmental, and phylogenetic perpetrators of metastatic leishmaniasis.
Hartley MA, Drexler S, Ronet C, Beverley SM, Fasel N
Trends Parasitol 2014 Aug;30(8):412-22. Epub 2014 Jun 20 doi: 10.1016/j.pt.2014.05.006. PMID: 24954794Free PMC Article
Leishmaniases in Greece.
Ntais P, Sifaki-Pistola D, Christodoulou V, Messaritakis I, Pratlong F, Poupalos G, Antoniou M
Am J Trop Med Hyg 2013 Nov;89(5):906-15. Epub 2013 Sep 23 doi: 10.4269/ajtmh.13-0070. PMID: 24062479Free PMC Article
Leishmaniasis.
Piscopo TV, Mallia Azzopardi C
Postgrad Med J 2007 Feb;83(976):649-57. doi: 10.1136/pgmj.2006.047340corr1. PMID: 17396274Free PMC Article

Diagnosis

Post-kala-azar dermal leishmaniasis.
Pathania YS, Budania A
QJM 2022 Jan 5;114(11):824-825. doi: 10.1093/qjmed/hcab236. PMID: 34499181
Cutaneous Leishmaniasis.
Crecelius EM, Burnett MW
J Spec Oper Med 2021 Spring;21(1):113-114. doi: 10.55460/IMV2-JGWD. PMID: 33721318
Leishmaniasis.
Burza S, Croft SL, Boelaert M
Lancet 2018 Sep 15;392(10151):951-970. Epub 2018 Aug 17 doi: 10.1016/S0140-6736(18)31204-2. PMID: 30126638
Making sausages.
Wortmann G
J Travel Med 2014 Mar-Apr;21(2):77-8. doi: 10.1111/jtm.12093. PMID: 24593021
Periungual leishmaniasis.
Gomes CM, Morais OO, Leite AS, Soares KA, Motta Jde O, Sampaio RN
An Bras Dermatol 2012 Jan-Feb;87(1):148-9. doi: 10.1590/s0365-05962012000100024. PMID: 22481669

Therapy

Leishmaniasis.
Burza S, Croft SL, Boelaert M
Lancet 2018 Sep 15;392(10151):951-970. Epub 2018 Aug 17 doi: 10.1016/S0140-6736(18)31204-2. PMID: 30126638
Leishmaniasis.
Von Stebut E
J Dtsch Dermatol Ges 2015 Mar;13(3):191-200; quiz 201. doi: 10.1111/ddg.12595. PMID: 25721626
Making sausages.
Wortmann G
J Travel Med 2014 Mar-Apr;21(2):77-8. doi: 10.1111/jtm.12093. PMID: 24593021
Periungual leishmaniasis.
Gomes CM, Morais OO, Leite AS, Soares KA, Motta Jde O, Sampaio RN
An Bras Dermatol 2012 Jan-Feb;87(1):148-9. doi: 10.1590/s0365-05962012000100024. PMID: 22481669
Therapy of cutaneous leishmaniasis.
Lee SA, Hasbun R
Int J Infect Dis 2003 Jun;7(2):86-93. doi: 10.1016/s1201-9712(03)90002-6. PMID: 12839708

Prognosis

Cutaneous leishmaniasis: A great imitator.
Gurel MS, Tekin B, Uzun S
Clin Dermatol 2020 Mar-Apr;38(2):140-151. Epub 2019 Oct 24 doi: 10.1016/j.clindermatol.2019.10.008. PMID: 32513395
Changes in the Epidemiology of Cutaneous Leishmaniasis in Northeastern Iran.
Farash BRH, Shamsian SAA, Mohajery M, Fata A, Sadabadi F, Berenji F, Mastroeni P, Poustchi E, Moghaddas E, Sangani GS, Farnoosh G
Turkiye Parazitol Derg 2020 Mar 20;44(1):52-57. doi: 10.4274/tpd.galenos.2019.6137. PMID: 32212595
Cutaneous and mucocutaneous leishmaniasis: Clinical perspectives.
Handler MZ, Patel PA, Kapila R, Al-Qubati Y, Schwartz RA
J Am Acad Dermatol 2015 Dec;73(6):897-908; quiz 909-10. doi: 10.1016/j.jaad.2014.08.051. PMID: 26568335
The current status of cutaneous leishmaniasis in Morocco.
Tlamçani Z, Er-Rami M
Turkiye Parazitol Derg 2014;38(1):5-8. doi: 10.5152/tpd.2014.1401. PMID: 24659693
Leishmaniases in Greece.
Ntais P, Sifaki-Pistola D, Christodoulou V, Messaritakis I, Pratlong F, Poupalos G, Antoniou M
Am J Trop Med Hyg 2013 Nov;89(5):906-15. Epub 2013 Sep 23 doi: 10.4269/ajtmh.13-0070. PMID: 24062479Free PMC Article

Clinical prediction guides

Post kala-azar dermal leishmaniasis: A threat to elimination program.
Gedda MR, Singh B, Kumar D, Singh AK, Madhukar P, Upadhyay S, Singh OP, Sundar S
PLoS Negl Trop Dis 2020 Jul;14(7):e0008221. Epub 2020 Jul 2 doi: 10.1371/journal.pntd.0008221. PMID: 32614818Free PMC Article
Changes in the Epidemiology of Cutaneous Leishmaniasis in Northeastern Iran.
Farash BRH, Shamsian SAA, Mohajery M, Fata A, Sadabadi F, Berenji F, Mastroeni P, Poustchi E, Moghaddas E, Sangani GS, Farnoosh G
Turkiye Parazitol Derg 2020 Mar 20;44(1):52-57. doi: 10.4274/tpd.galenos.2019.6137. PMID: 32212595
Otolaryngological manifestations of leishmaniosis.
Kurnatowski P, Moroz J
Otolaryngol Pol 2016 Oct 31;70(5):2-6. doi: 10.5604/00306657.1203550. PMID: 27935542
Leishmaniasis.
Von Stebut E
J Dtsch Dermatol Ges 2015 Mar;13(3):191-200; quiz 201. doi: 10.1111/ddg.12595. PMID: 25721626
The immunological, environmental, and phylogenetic perpetrators of metastatic leishmaniasis.
Hartley MA, Drexler S, Ronet C, Beverley SM, Fasel N
Trends Parasitol 2014 Aug;30(8):412-22. Epub 2014 Jun 20 doi: 10.1016/j.pt.2014.05.006. PMID: 24954794Free PMC Article

Recent systematic reviews

Systematic Review: Re-emergence of human leishmaniasis in the Balkans.
Vaselek S
Trop Med Int Health 2021 Oct;26(10):1189-1199. Epub 2021 Jul 26 doi: 10.1111/tmi.13653. PMID: 34265146
Three decades of clinical trials on immunotherapy for human leishmaniases: a systematic review and meta-analysis.
Mota CA, Oyama J, Souza Terron Monich M, Brustolin AÁ, Perez de Souza JV, Murase LS, Ghiraldi Lopes LD, Silva Santos TD, Vieira Teixeira JJ, Verzignassi Silveira TG
Immunotherapy 2021 Jun;13(8):693-721. Epub 2021 Apr 15 doi: 10.2217/imt-2020-0184. PMID: 33853344
Leishmaniasis and Trace Element Alterations: a Systematic Review.
Taghipour A, Abdoli A, Ramezani A, Abolghazi A, Mofazzal Jahromi MA, Maani S, Heidar Nejadi SM, Rasti S, Shams M, Ghasemi E
Biol Trace Elem Res 2021 Oct;199(10):3918-3938. Epub 2021 Jan 6 doi: 10.1007/s12011-020-02505-0. PMID: 33405078
Cutaneous manifestations and considerations in COVID-19 pandemic: A systematic review.
Seirafianpour F, Sodagar S, Pour Mohammad A, Panahi P, Mozafarpoor S, Almasi S, Goodarzi A
Dermatol Ther 2020 Nov;33(6):e13986. Epub 2020 Aug 6 doi: 10.1111/dth.13986. PMID: 32639077Free PMC Article
Honey as a topical treatment for wounds.
Jull AB, Cullum N, Dumville JC, Westby MJ, Deshpande S, Walker N
Cochrane Database Syst Rev 2015 Mar 6;2015(3):CD005083. doi: 10.1002/14651858.CD005083.pub4. PMID: 25742878Free PMC Article

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